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[Original research] [Stomatology]
Igor Bazikov; Valentina Botasheva; Olga Sumkina; Fahriel Muharamov; Nadezhda Penkova; Vera Lukinova; Elena Chekrygina; Dmitry Domenyuk;
Cultured allogeneic fibroblasts were obtained from gingival biopsy that have been used in the treatment of periodontal disease. Histological studies of periodontal lesion were conducted in an experiment. It was revealed that the animals without treatment developed the picture of diffuse purulent periodontitis with severe destructive changes and formation of a deep defect on the 7th day. In the treatment with «Metragil-Denta» focal purulent inflammation developed around the lesion, destructive changes were observed with the formation of a shallow defect. In the treatment with «Regenerin» serous periodontitis developed in the periodontium. The most pronounced reparative processes have been reported with the use of cultured fibroblasts. Histological examination revealed increased fibrillogenesis with the formation of young connective tissue.
References:
1. Bazikov I. A., Ghoukassian A. L., Zelenskiy V. A. Medicinskiy vestnik Severnogo Kavkaza. – Medical News of the North Caucasus. 2011;22(2):59-60.
2. Bazikov I. A., Beyer E. V., Klimanovich I. V., Avakova T. A., Hatkov E. M., Ghoukassian A. L., Bazikov F. I. Izuchenie ostroi toksichnosti razrabo-tannogo regenerativnogo narugnogo sredstva / 17th annual Medicine Week Stavropol. Collected articles. Stavropol: RA «Expo Media». 2013. Р. 140-141.
3. Bazikov I. A., Klimanovich I. V., Avakova T. A., Hatkov E. M., Ghoukassian A. L. Razrabotka I izgotovlenie regeneriruuschih substancii iz extrakta kletok placenti givotnogo proishogdeniya 17th annual Medicine Week Stavropol. / Collected articles. Stavropol: RA «Expo Media». 2013. Р. 138-139.
4. Bazikov I. A., Klimanovich I.V., Pen’kova N. I., Magonov M. M., Avakova T. A., Lysogora L. V., Hatkov E. M., Seiranidu Z. A., Ghoukassian A. L., Deryazhentseva M. A., Kalinkin N. I., Bazikov F. I. Medicinskiy vestnik Severnogo Kavkaza. – Medical News of the North Caucasus. 2013;8(3):14-18.
5. Bazikov I. A., Sumkina O. B., Botasheva V. S., Klimanovich I. V., Pen’kova N. I., Chekrygina E. V., Ghoukassian A. L., Deryazhentseva M.A., Kalin-kin N. I., Bazikov F. I. Medicinskiy vestnik Severnogo Kavkaza. – Medical News of the North Caucasus. 2013;8(4):9-13.
6. Bazikov I. A., Omel’yanchuk P. U. RF Patent № 2469704: MPK7 In 07 C 05.12,9/00 /; patentee NPO «cell technology.»
7. Gluschenko E. V. and others. Jurnal ekspere-mental`noiy biologii I mediciniy. – Bulletin of Experimental Biology and medicine. 1996;5:575-577.
8. Grudyanov A. I., Erohin I. A., Byakova S. F. Novoe v stomatologii. – New in dentistry. 2001;8(98):72-77.
9. Grudyanov A. I., Erohin I. A., Bezrukov I. V. Parodontologiya. – Periodontology. 2002;1-2(23):12-16.
10. Novikova I. A. Medicina I Biotehnologiya. – Medicine and Biotechnology. 2003;3:1-5.
11. Novikova I. A., Ron’ G. I., Glinskikh N. P., Medvedev S. Y. Institut Stomatolodii. – Institute of Dentistry. 2003;2(19):43-45.
12. Runova T. S. Using cultured allofibroblastov in the complex treatment of periodontal diseas. M.; 2000. P. 18.
13. Tumanov V. P., Dmitriev L. A., Runova G. S. and others. Science-practice: Proceedings of the scientific session ZNIIS dedicated to the 35th anniversary of institute. M.;1998. P. 164-167.
Keywords: fibroblasts, periodontal, histological studies, regeneration