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[Experimental medicine]
Evgeny Shchetinin; Sergey Sirak; Anna Khodzhayan; Natalia Radzievskaya; Gregory Petrosyan;
In the course of experimental pathophysiological study the processes of regeneration in the alveolar socket of the extracted tooth of a rat is studied. In the experiment we used 42 rats. In the control group (21 animal) the alveolar socket of the extracted lower incisor was under a blood clot, in the main group (21 animal) it was filled with the drug «Tachocomb». The results of the research have shown that introduction of the drug «Tachocomb» into an alveolar socket of the extracted lower incisor of a rat causes an increase in proliferative activity of the cellular components of the connective tissue and bone marrow. In the main group the structure of the regenerate in alveolar socket of the extracted tooth acquires the features inherent in mature spongy bone earlier than in the control group.
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Keywords: regeneration, tooth, alveolar socket, inflammation, experiment