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https://doi.org/10.14300/mnnc.2025.20069

Possibilities of monitoring and stimulating of the long-term non-healing wounds using an integrated approach

[Surgery]
Oksana Vladimirova; Peter Lavreshin; Sergey Minaev; Lev Brusnev; Anton Vladislavovich Terehin; Muradin Mustafaevich Vergasov; Vladimir Vladimirov; Ivan Aleksandrovich Zybinsky;

A comparative analysis of the treatment results was performed for 52 patients with the long-term non-healing wounds, 40–85 years, who have been in inpatient and outpatient treatment. The study group underwent complex surgical treatment using a cold plasma flow, aerogel chitosan wound dressings and a gel with chitosan, lidocaine and an antiseptic. For a systemic stimulating effect, Ximedon was used. The dynamics of healing and the patient’s condition were monitored in a standard electronic database of a medical institution, and in parallel, data were entered into the personalized electronic program «Dispensary Card Wounds Scars». There was a reduction in the healing time from an average of 35.09±6.07 days in the control group to 21.35±3.63 days in the study group, a significant decrease in bacterial contamination and the risk of complications.

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Keywords: cold plasma flow, granulating wound, wound healing, chronic wound, wound stimulation, chitosan