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Effectiveness of endoscopic ligation of varicose veins of the esophagus and transjugular intrahepatic porto-systemic shunt in the prevention of repeated bleedings in patients with ascites included on the waiting list for liver transplantation

[Surgery]
Roman Vyacheslavovich Korobka; Sergey Vladimirovich Gautier; Yury Khoronko; Viktor Dmitrievich Pasechnikov; Natalia Germanovna Sapronova; Mikhail Vladimirovich Malevanny; Ekaterina S. Pak; Dmitry Viktorovich Pasechnikov; Elena Valerievna Tadiyeva;

A retrospective comparative study was conducted on the effectiveness of preventing recurrent bleeding in patients with ascites refractory (n=96) and not refractory to diuretic therapy (n=26), included in the waiting list for liver transplantation, and undergoing endoscopic ligation of esophageal varices, or TIPS implantation. There were no significant differences in clinical, laboratory, demographic parameters, MELD scores, Child-Turcotte-Pugh classes of liver cirrhosis, or rates of detection of medium-sized and large varices in subgroups of patients with different methods of recurrent bleeding preventing in both forms of ascites.

The effectiveness of recurrent bleeding preventing is higher with TIPS implantation than with endoscopic ligation of varicose nodes in both forms of ascites.

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Keywords: waiting list for liver transplantation, ascites, variceal rebleeding, secondary prevention of bleeding, endoscopic band ligation of varices, TIPS implantation


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Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy