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https://doi.org/10.14300/mnnc.2023.18095

Jaw bone remodeling after the surgical treatment of chronic periodontitis: experimental study

[Experimental medicine]
Sergey Sirak; Vadim Nikolaevich Lenev; Alina Rashitovna Romanenko; Ekaterina Sergeevna Sirak; Elizaveta Evgenievna Shchetinina; Gregory Petrosyan; Evgeny Shchetinin;

The article presents the results of a study of the secondary restructuring timing of periodontal tissues after surgical treatment the moderate periodontitis in the near and long term. In the experiment, 70 adult white laboratory male rats were used, randomly distributed into 3 research groups: main (30 animals), control (30 animals) and intact (10 animals). After modeling of the chronic periodontitis according to the author’s method, curettage was performed to remove granulations and pathologically altered tissues with wound filling in the main group with granules of two-phase calcium phosphate ceramics, in the control group the wound was healed under the blood clot, evaluating the results in the immediate (7–30 days) and distant 60–120 days) periods. As a result of the study, it was found that with mechanical damage to the compact layer of the jaw, destructive and regenerative processes occur in the bone, leading to a long-term restructuring, which in the main group proceed more intensively compared to reactive processes in the control group, where the compaction of the wall of the tooth socket does not finished even by 6 months. Removal of the connective tissue granulations, the pathologically altered interdental bone septum and ceramics contributes not only to the relief of inflammation in the periodontium, but also to the restoration of the periodontal attachment in the apical and cervical parts of the tooth root, which provides optimal conditions for physiological reparative regeneration.

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Keywords: periodontitis, curettage, osteogenesis, bone tissue, regeneration, experiment