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Dynamics of indicators of the prooxidant and antioxidant blood system in patients with pemphigus vulgaris

[Original research] [Dermatology]
Feras Mohammed Sami Al Asfari; Evgeny Shchetinin; Sergey Sirak; Elena Mikhailovna Maksimova; Maria Perikova; Nikolai Budzinski;

The article presents the results of research on the dynamics of indicators of pro- (the level of malondialdehyde in erythrocytes and the level of average mass molecules in the blood serum) and the antioxidant system of the blood (the level of reduced glutathione in erythrocytes and the activity of ceruloplasmin in the blood serum) in patients with Pemphigus Vulgaris (PV) of varying severity. The data obtained indicate significant shifts in the parameters of the pro- and antioxidant blood system in patients with PV, which correlated with the severity of the pathological process.


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Keywords: pemphigus vulgaris, blood antioxidant system

Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy