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Evaluating the effectiveness of glucocorticosteroid monotherapy for the treatment of keloid and hypertrophic scars

[Original research] [Surgery]
Oksana Vladimirova; Peter Lavreshin; Vladimir Vladimirov; Evgeny Pechenkin; Sofia Korablina; Alina Nikolaevna Grigorova; Ilyas Korkmazov; Mariam Nyurchikovna  Machukova;

Treatment of pathological excess scars is one of the urgent problems in rehabilitating patients after injuries and operations. A comparative analysis of the treatment results of 260 patients who developed pathological scars after injuries using glucocorticosteroid hormone (triamcinolone acetonide) was carried out. Stable remission in all patients with keloid scars was achieved. Monotherapy with triamcinolone in patients with hypertrophic scars did not show high efficiency. A good but short-term effect was conducted, including a reduction in connective tissue and scar size with a noticeable analgesic and antipruritic effect. However, later hyperplasia of the scar was noted. Thus, the analysis of the data obtained indicates a greater pathognomonic and expediency of monotherapy with triamcinolone for the treatment of keloid scars. In contrast, its use in hypertrophic scars is possible only as part of combined anti-scar therapy.

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Keywords: keloid scar, hypertrophic scar, triamcinolone acetonide, treatment


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Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy