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Using confocal microscopy of the eye cornea, we studied the prevalence of distal polyneuropathy and assessed the relationship between the severity of its manifestations and the degree of impaired carbohydrate metabolism in 41 patients with obesity, pre-diabetic dysglycemia, and type 2 diabetes mellitus (DM). Deviations from the norm of the coefficients of anisometropy and asymmetry, directly correlating with the indicators of glycemia, are reliably often established. Comparable values of the asymmetry coefficient in patients with type 2 DM and prediabetes allow us to consider it as a predictor of the onset or early marker of dysmetabolic polyneuropathy.
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Keywords: neuropathy, metabolic syndrome, confocal microscopy of the cornea of the eye