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Prediction of the failure of colonic anastomoses during resection of the left parts of the colon and rectum

[Surgery]
Sharip Omaraskhabovich Darbishgadzhiev; Denis Vladimirovich Vikhrev; Anatoly Afanasevich Baulin; Oleg Igorevich Kaganov; Vyacheslav Gudoshnikov; Sergey Alexandrovich Nikishin;

The failure of colonic anastomoses remains a severe and common complication after the restoration of the naturalness of the digestive tract. The aim of the research was to study the main risk factors for the development and working out a scale for predicting the failure of colonic anastomoses in the treatment of colorectal cancer. The study included 418 patients with resection of the left half of the colon and rectum and subsequent restoration of the continuity of the intestinal tube. After binary regression analysis, 6 predictors were included in the prognostic model: preoperative radiation therapy, the level of anastomosis formation, hemoglobin concentration in the blood less than 90 g/l, albumin content in the blood less than 27 g/l, combined and simultaneous interventions, the duration of the operation more than 140 minutes. The value of the correct classifications was 92.6 %, which reflects the good predictive ability of the proposed scale.

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Keywords: failure of anastomose, forecasting, risk factors, colon anastomose, rectum resection, resection of the left part of the colon


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