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Federal service for surveillance over non-violation of the legislation in the sphere of mass communications and protection of cultural heritage.
ISSN 2073-8137
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Clinical significance of pro-inflammatory interleukins in newborns with hypoxic-ischemic CNS damage

[Abstracts]
Lyudmila Barycheva; Aminat Idrisova; Ekaterina Sergeevna Kuzmina; Oleg Agranovich;

Pro-inflammatory interleukins in blood serum were studied in 45 newborns with hypoxic-ischemic defeats of the central nervous system. Revealed an increase in the levels of IL-1β and IL-6. High levels of IL-1β, IL6, IL-8, IL-18 were determined in children with unfavorable neurological outcomes of cerebral ischemia. The obtained data allow to consider an increase level of IL-1β and IL-6 in newborns as risk factors for adverse neurological outcomes of hypoxic-ischemic encephalopathy.

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References:
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https://doi.org/10.18502/ijrm.v17i5.4598
2. Jiang L. J., Xu Z. X., Wu M. F., Dong G. Q., Zhang L. L. [et al.]. Resatorvid protects against hypoxic-ischemic brain damage in neonatal rats. Neural. Regen. Res. 2020;15(7):1316-1325.
https://doi.org/10.4103/1673-5374.272615312
Заметки иЗ практики notes from practice
3. Xiong L. L., Xue L. L., Al-Hawwas M., Huang J., Niu R. Z. [et al.]. Single-nucleotide polymorphism screening and RNA sequencing of key messenger RNAs associated with neonatal hypoxic-ischemia brain damage. Neural. Regen. Res. 2020;15:86-95.
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https://doi.org/10.1186/s12887-018-1232-6
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Keywords: hypoxic-ischemic encephalopathy, pro-inflammatory interleukins


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