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[Original research] [Surgery]
Georgy Mildzikhov; Valeriy Totikov; Madina Pagieva; Zaurbek Totikov;
In an experimental study, a morphological analysis of microcirculatory changes in enteroenteroanastomosis in 72 rats was carried out. It was found that that the most pronounced microcirculatory disorders in the intestinal wall occur under the influence of mezaton, which contributes to the development of anastomotic leakage. The use of droperidol prevented the development of hypoxic tissue damage and promoted the stimulation of reproduction processes.
References:
1. Agaev E. K. prevention of insolvency of sutures of intestinal anastomoses by the method of permanent intracranial blockade of lymphotropic therapy. Vestnik hirurgii. – Journal of surgery. 2013;172(1):81-84. (In Russ.).
https://doi.org/10.24884/0042-4625-2013-172-1-081-084
2. Gorsky V. A., Agapov M. A., Klimov A. E., Andreev S. S. Problems of intestinal suture consistency. Prakticheskaya medicina. – Practical medicine. 2014;5(81):33-37. (In Russ.).
3. Mildzikhov G. U., Totikov V. Z., Pagieva M. K., Totikov Z. V. Analysis of microcirculatory disorders in the area formed by thin-colonic anastomosis. Infekcii v hirurgii. – Infections in surgery. 2017;2(16):3-5. (In Russ.).
4. Akhmetzyanov F. I., Egorov A. I., Valeev A. I. Treatment of insolvency of colorectal anastomosis sutures: is it Possible to preserve the anastomosis? Sibirskij onkologicheskij zhurnal. – Siberian cancer journal. 2018;17(1):92-98. (In Russ.).
https://doi.org/10.21294/1814-4861-2018-17-1-92-98
5. Totikov Z. V., Totikov V. Z., Kachmazov A. K., Medoev V. V., Kalicova M. V. [et al.]. Kubanskij nauchnyj medicinskij vestnik. – Kuban Scientific Medical Bulletin. 2013;4(139):109-111. (In Russ.).
Keywords: enteroenteroanastomosis, microcirculatory disorders, destructive processes, morphological analysis, vasoactive drugs