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EBSCO

https://doi.org/10.14300/mnnc.2021.16047

Platelet-rich autoplasma use at early stages of wound healing to prevent pathological scar development

[Abstracts]
Oksana Vladimirova; Peter Lavreshin; Vladimir Ivanovich Vladimirov; Alina Nikolaevna Grigorova; Vakhtang Gobejishvili; Alexander Dolgalev; Sergey Timofeev; Sofia Korablina;

Pathological excess scar treatment is currently viewed as one of the most urgent issues with no single standard solution. We investigated the effectiveness of platelet-rich autoplasma use to stimulate wound healing. Seventy-six patients were assigned to two equivalent groups: control and main. The dynamics revealed a high efficiency of the plasma autostimulation method, which reduced the time of inpatient treatment, accelerated healing with a decrease in the effects of inflammation in the area of injury, stabilized angiogenesis, fibroplasia, and epithelialization, and, as a consequence, decreased the developmental rate of a pathological scar.

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Keywords: pathological scars, keloid, hypertrophic scar, autostimulation, scar diary, platelet-rich plasma, prevention of pathological scar formation, stimulation of healing