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Effect of kodivak on the dynamics of the wounding process in experimental modeling of infected wounds in rats
[Experimental medicine]
Elina Ramizovna Matvienko; Vladimir Baturin; Elena Aleksandrovna Shmeleva; Karine Elbekyan;
The model of an infected wound in rats showed a decrease in the intensity of inflammation in the first 4 days with an acceleration of proliferation processes with preliminary administration of Kodivak. In the subsequent period from 4 to 9 days after wound modeling in animals that received Kodivak, the relative loss of wound area was significantly higher than in the control group.
References:
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2. Wiles S. All models are wrong, but some are useful: Averting the «microbial apocalypse». Virulence. 2015;6(8):730-732. https://doi.org/10.1080/21505594.2014.1001238
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4. Shmeleva E. A., Baturina I. G., Paramonova Yu. A., Perelygma O. V., Korzhenkova M. P., Sviridov V. V. The humoral immunity against diphtheria. Journal of Microbiology Epidemiology Immunobiology. 2007;4:9-15.
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Keywords: Kodivak, regeneration, vaccine, infection, wound
Founders:
Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy