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ISSN 2073-8137

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The quality of life in patients with ruptured multiple cerebral aneurysms after endovascular treatment

Anna Anatolyevna Oleinik; Natalia Evgenievna Ivanova; Sergey Anatolievich Goroshchenko; Arkady Aleksandrovich Ivanov; Ekaterina Anatolyevna Oleynik; Alexey Yurievich Ulitin; Aleksey Yurevich Ivanov;

The quality of life (QOL) was studied in patients with ruptured multiple cerebral arterial aneurysms (AA) in the late postoperative period after endovascular treatment. The study included 86 cases with multiple AAs with a history of one or more subarachnoid hemorrhages (SAH); the comparison group included 86 observations with unruptured multiple AAs. All patients underwent endovascular treatment of multiple AAs. QoL in the late postoperative period was assessed from 6 months to 2 years after surgery using the SF-36 questionnaire. A decrease in the International Classification of Functioning (ICF) indices was revealed in the main group compared to the comparison group in the domains b2151 (eyelid function), b7301 (muscle function of one limb), b7302 (muscle function of one side of the body), d4501 (long distance walking) (p <0.05). Deterioration of indicators in patients with a history of SAH was on the subscale SF (Social functioning) (p <0.05), RF (Role functioning due to physical condition) (p=0.03). The factors influencing the patients’ status after SAH were the age of patients (from 61 to 70 years), the presence of complications of the acute period of SAH, complications of surgical interventions. In the long-term postoperative period, satisfactory QOL indicators achieved in patients with SAH. To improve the quality of life, it is necessary to carry out rehabilitation in patients with neurological symptoms.



1. Jabbarli R., Dinger T. F., Darkwah Oppong M., Pierscianek D., Dammann P. [et al.]. Risk factors for and clinical consequences of multiple intracranial aneurysms. Stroke. 2018;49(4):848-855. https://doi.org/10.1161/STROKEAHA.117.020342
2. Roethlisberger M., Achermann R., Bawarjan S., Stienen M. N., Fung C. [et al.]. Swiss SOS Study Group. Predictors of occurrence and anatomic distribution of multiple aneurysms in patients with aneurysmal subarachnoid hemorrhage. World Neurosurg. 2018;111:e199-e205. https://doi.org/10.1016/j.wneu.2017.12.046
3. McDowell M. M., Zhao Y., Kellner C. P., Barton S. M., Sussman E. [et al.]. Demographic and clinical predictors of multiple intracranial aneurysms in patients with subarachnoid hemorrhage. J. Neurosurg. 2018;128(4):961-968. https://doi.org/10.3171/2017.1.JNS162785
4. Brain aneurysm surgery / Pod red. V. V. Krylova. Moskva, 2011. Tom I. (In Russ.).
5. Song J. P., Ni. W., Gu Y. X., Zhu W., Chen L. [et al.]. Epidemiological features of nontraumatic spontaneous subarachnoid hemorrhage in China: A nationwide hospital-based multicenter study. Chinese Med. J. 2017;130(7):776-781. https://doi.org/10.4103/0366-6999.202729
6. Roethlisberger M., Achermann R., Bawarjan S., Stienen M. N., Fung C. [et al.]. Swiss SOS group. Impact of Aneurysm Multiplicity on Treatment and Out-come. After Aneurysmal Subarachnoid Hemorrhage. Neurosurgery. 2019;1,84(6):e334-344. https://doi.org/10.1093/neuros/nyy331
7. Andersen C. R., Fitzgerald E., Delaney A., Finfer S. Systematic Review of Outcome Measures Employed in Aneurysmal Subarachnoid Hemorrhage (aSAH). Clin. Res. Neurocritical. Care. 2019;30(3):534-541. https://doi.org/10.1007/s12028-018-0566-0
8. Dammann P., Wittek P., Darkwah Oppong M., Hütter B. O., Jabbarli R. [et al.]. Relative health-related quality of life after treatment of unruptured intracranial aneurysms: long-term outcomes and influencing factors. Ther. Adv. Neurol. Disord. 2019;12:1-12. https://doi.org/10.1177/1756286419833492
9. Schwyzer L., Soleman E., Ensner R., Mironov A., Landolt H. [et al.]. Quality of life and outcome after treatment of ruptured cerebral aneurysms: Results of a single center in Switzerland. Acta Neurochir., Suppl. 2015;120:197-201. https://doi.org/10.1007/978-3-319-04981-6_34
10. Kolotvinov V. S., Sakovich V. P., Shamov A. Ju. Quality of life for patients operated on about cerebral aneurysms. Patologija krovoobrashhenija i kardiohirurgija. – Circulatory pathology and cardiac surgery. 2012;16(4):33-36. (In Russ.). https://doi.org/10.21688/1681-3472-2012-4-33-36
11. Greebe P., Rinkel G. J. E., Hop J. W. [et al.]. Functional outcome and quality of life 5 and 12.5 years after aneurysmal subarachnoid haemorrhage. J. Neurol. 2010;257(12):2059-2064.
12. Moon K., Albuquerque F. C., Ducruet A. F., Crowley R. W., McDougall C. G. Resolution of cranial neuropathies following treatment of intracranial aneurysms with the Pipeline Embolization Device. J. Neurosurg. 2014;121(5):1085-1092. https://doi.org/10.3171/2014.7.JNS132677
13. Imai H., Watanabe K., Miyagishima T., Yoshimoto Y., Kin T. [et al.]. The outcome of a surgical protocol based on ischemia overprotection in large and giant aneurysms of the anterior cerebral circulation. Neurosurg. Rev. 2016;39(3):505-517. https://doi.org/10.1007/s10143-016-0721-z
14. Luzzi S., Gallieni M., Del Maestro M., Trovarelli D., Ricci A. [et al.]. Giant and Very Large Intracranial Aneurysms: Surgical Strategies and Special Issues. Acta Neurochir. Suppl. 2018;129:25-31. https://doi.org/10.1007/978-3-319-73739-3_4
15. Xu L., Deng X., Wang S., Cao Y., Zhao Y. [et al.]. Giant Intracranial Aneurysms: Surgical Treatment and Analysis of Risk Factors. World Neurosurg. 2017;102:293-300. https://doi.org/10.1016/j.wneu.2017.03.055
16. Spetzler R. F., McDougall C. G., Zabramski J. M., Albuquerque F. C., Hills N. K. [et al.]. The barrow ruptured aneurysm trial: 6-year results. J. Neurosurg. 2015;123:609-617. https://doi.org/10.3171/2014.9.JNS141749
17. Taufique Z., May T., Meyers E., Falo C., Mayer S. A. [et al.]. Meyers Predictors of poor quality of life 1 year after subarachnoid hemorrhage. Neurosurgery. 2016;78(2):256-264. https://doi.org/10.1227/NEU.0000000000001042
18. Czapiga B., Kozba-Gosztyla M., Czapiga A., Jarmundowicz W., Rosinczuk-Tonderys J. [et al.]. Recovery and quality of life in patients with ruptured cerebral aneurysms. Rehabilitat. Nursing. 2014;39(5):250-259. https://doi.org/10.1002/rnj.125

Keywords: aneurysms of cerebral vessels, cerebral aneurysms, multiple aneurysms, distant postoperative period, endovascular treatment

Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy