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ISSN 2073-8137

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Morphological changes in the organs of immunogenesis under the influence of an experimental factor

[Experimental medicine]
Anatoly Trofimovich Yakovlev; Alexandr Korobkeev; Elena A. Zagorodneva; Natalia Gennadievna Krayushkina; Diana Pavlovna Lavrova; Natalia Ivanovna Kovaleva; Ekaterina Vladimirovna Vlasova;

In the course of an experimental morphological study, the regularities of morphological changes in the сentral and peripheral organs of the immune system were established when the body was exposed to an alternating electromagnetic field of industrial frequency. After 7-day irradiation of animals, an almost two-fold increase in the area of the ventro-dorsal projection of the thymus was revealed with a decrease in the relative area of the cortex by one third. Morphological changes in the lymph nodes concerned both external parameters and internal structures. After 14 days of irradiation, the organs of immunogenesis acquired resistance to the effects of the electromagnetic field while maintaining a high proliferative activity of lymphoid tissue.


1. Sato Y., Kiyohara K., Takehara S., Kojimahara N. Ecological study on the penetration of induction heating cookers and birth outcomes in Japan. AIMS Public Health. 2020;7(2):336-343. https://doi.org/10.3934/publichealth.2020028
2. Paolucci T., Pezzi L., Centra A. M., Giannandrea N., Bellomo R. G., Saggini R. Electromagnetic Field Therapy: A Rehabilitative Perspective in the Management of Musculoskeletal Pain – A Systematic Review. Journal Pain Research. 2020;13:1385-1400. https://doi.org/10.2147/JPR.S231778
3. Zymantiene J., Juozaitiene V., Zelvyte R., Oberauskas V., Spancerniene U. [et al.]. Effect of Electromagnetic Field Exposure on Mouse Brain Morphological and Histopathological Profiling. Journal of Veterinary Research. 2020;64(2):319-324. https://doi.org/10.2478/jvetres-2020-0030
4. Ouyang J., Zhang B., Kuang L., Yang P., Du X. [et al.]. Pulsed Electromagnetic Field Inhibits Synovitis via Enhancing the Efferocytosis of Macrophages. BioMed Research International. 2020;2020:4307385. https://doi.org/10.1155/2020/4307385
5. Simkó M., Mattsson M. O. Extremely low frequency electromagnetic fields as effectors of cellular responses in vitro: possible immune cell activation. Journal of Cellular Biochemistry. 2004;93(1):83-92. https://doi.org/10.1002/jcb.20198
6. An G. Z., Xu H., Zhou Y., Du L., Miao X. [et al.]. Effects of long-term 50Hz power-line frequency electromagnetic field on cell behavior in Balb/c 3T3 cells. PLoS ONE. 2015;10(2):e0117672. https://doi.org/10.1371/journal.pone.0117672
7. Li B. L., Li W., Bi J. Q., Zhao J. G., Qu Z. W. [et al.]. Effect of long-term pulsed electromagnetic field exposure on hepatic and immunologic functions of rats. Wiener Klinische Wochenschrift. 2015;127(23-24):959-962. https://doi.org/10.1007/s00508-015-0732-8
8. Krayushkin A. I., Perepelkin A. I., Alexandrova L. I., Zagorodneva E. A., Krayushkina N. G. Spatial organization in the cross-section plane of extended structures of rabbit lymph nodes under the influence of an alternating electromagnetic field of industrial frequency. Volgogradskii naychno-Medicinskii zhurnal. – Volgograd Scientific and medical Journal. 2016;(4):11-17. (In Russ.).

Keywords: variable electromagnetic fields of industrial frequency, thymus, lymph nodes

Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy