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of the North Caucasus
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ISSN 2073-8137

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Experimental evaluation of the effectiveness of biological stimulation of adhesiogenesis in residual pleural cavities

[Experimental medicine]
Anton Kalashnikov; Svetlana Kalashnikova; Aleksandr Aleksandrovich Vorobyov; Dmitry Shamilovich Salimov; Salikhat Shamilovna Aydaeva;

Data on the combined use of plasmolifting and lipofilling as a method of biological stimulation of adhesiogenesis in the experimental treatment of residual pleural cavities in chronic pleural empyema in 300 male rats are presented. Co-administration of autologous homogenized fat emulsion and platelet-rich plasma to rats resulted in a 33.4-fold reduction in mortality (p<0.001) compared to the comparison group without treatment (negative control) and 3.9-fold (p<0.05).


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Keywords: adhesiogenesis, residual pleural cavity, pleural empyema, lipofilling, PRP technology

Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy