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Special aspects of structure and immunohistochemical analysis of paradental cyst with difficult eruption of the third mandibu

[Stomatology]
Andrey Andreevich Zhevlakov; Irina Borodulina; Gennady Grebnev; Andrey Igorevich Yakovenko; Sergey Sirak; Vadim Nikolaevich Lenev; Sergey Rubnikovich;

The article deals with immunohistochemical features of the structure of the shell of a paradental cyst in difficult eruption of the lower third molars. Out of 40 patients 3 groups were formed with paradental, radicular and follicular forms of cysts. Immunohistochemical study of cysts shells using markers Ki67, P53, LCA and VEGF, revealed absence of signs of tumor transformation, as well as the inflammatory nature of radicular and paradental cysts with enhanced angiogenesis, maturation and proliferation of granulation tissue.

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References:
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2. Colgan C. M., Henry J., Napier S. S., Cowan C. G. Paradental cysts: a role for food impaction in the pathogenesis? A review of cases from Northern Ireland. British Journal of Oral and Maxillofacial Surgery. 2002;40(2):163-168. https://doi.org/10.1054/bjom.2001.0750
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8. Knight E. T., Seymour G. J., Cullinan M. P., Faggion C. M., Liu J. Risk factors that may modify the innate and adaptive immune responses in periodontal diseases. Periodontology 2000. 2016;1(71):22-51.
9. Saravana G. H. L., Subhashraj K. Cystic changes in dental follicle associated with radiographically normal impacted mandibular third molar. British Journal of Oral and Maxillofacial Surgery. 2018;46(7):552-553. https://doi.org/10.1016/j.bjoms.2008.02.008

Keywords: paradental cyst, radicular cyst, follicular cyst, immunohistochemical studу


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