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https://doi.org/10.14300/mnnc.2020.15046

Microflora of the respiratory tract in children with cystic fibrosis of the Stavropol territory

[Cystic fibrosis]
Ella Vodovozova; Larisa Ledeneva; Inna Samvelovna Grigoryants; Elena Alexandrovna Enina;

Chronic respiratory infection in cystic fibrosis is a leading factor in determining the prognosis of the disease. Thе work investigated the spectrum of the microflora of the respiratory tract in children of the Stavropol Territory suffering from cystic fibrosis. The microflora was determined in sputum, deep smears from the posterior pharyngeal wall, bronchial secretions obtained during bronchoscopy in 54 patients with cystic fibrosis aged from 1 to 18 years. In the period from 2015 to 2018, the leading role of St. aureus, Ps. aeruginosa and Str. pyogenes was revealed. Moreover, a decrease in the share of St. aureus (from 60.8 to 36.5 %), Str. pyogenes (from 15.6 to 11.5 %) and the growth of Ps. aeruginosa (from 15.7 to 26.9 %) is noted. Thus, in the Stavropol Territory, infection with gram negative flora is growing in children with cystic fibrosis, while Ps. aeruginosa is of particular concern.

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Keywords: cystic fibrosis, airway microflora