Medical news
of the North Caucasus
Scientific journal
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Series ПИ #ФС 77-26521.
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ISSN 2073-8137

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The prevalence of single-nucleotide polymorphisms CYP2С19*2 and CYP2С19*3 in russians population of Stavropol territory

Anna Tsarukyan; Vladimir Baturin;

A study of the prevalence of CYP2C19*2 and CYP2C19*3 in the russian ethnic group of Stavropol Territory has been carried out. The total carrier frequency of the «slow» CYP2С19 alleles studied was 42 %. The results obtained may assist in making decisions on the use of pharmacogenetic examination for selection of the dosage regimens for CYP2С19 drug substances.


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Keywords: pharmacogenetics, cytochrome P450, CYP2C19, genetic polymorphism

Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy