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https://doi.org/10.14300/mnnc.2017.12075

The interconnection acid-base blood balance and dysbiosis in children with chronic constipation

[Surgery]
Igor Kirgizov; Sergey Minaev; Alexandr Kachanov;

Interconnection of correlations of the acid-base blood balance with dysbiosis in 121 children with chronic constipation was found in the study. Metabolic acidosis is revealed with a high lactate concentration, emaciation of the organism buffer systems on the lowering background of main blood electrolytes and dehydration. And in its turn it takes place on the marked translocation of the intestinal microflora. The largest changes in the acid-base balance can be considered as a factor of the critical conditions in case of decompensated form of chronic constipation in this group of patients. The exposed changes must be taken into account not only while carrying out the intensive therapy of the occurred complications, but in case of conducting of conservative methods of correction of the disease. The lactate level in the blood can serve as a criterion of the efficiency of the operation in children with chronic constipation. Also it can be testify to the development of critical conditions.

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Keywords: chronic constipation, dysbiosis, acid-base blood balance, children