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Medical news
of the North Caucasus
Scientific journal
Mass media registration certificate dated December 7, 2006.
Series ПИ #ФС 77-26521.
Federal service for surveillance over non-violation of the legislation in the sphere of mass communications and protection of cultural heritage.
ISSN 2073-8137
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Results of treatment of serious ovarian cancer at the use of different schemes of neoadyuvant chemotherapy

[Abstracts]
Galina Nerodo; Oksana Kravtsova; Vera Nikitina; Ekaterina Verenikina; Ivan Nikitin;

Ovarian cancer is an extremely aggressive and unpredictable disease that affects women of all ages. We compared morphological structures of malignant serous ovarian tumors and the results of treatment in a group without chemotherapy and after neoadjuvant chemotherapy regimens: CAP and CMFV. The study included patients with stage III–IV disease, identical in degree of malignant process, age, general condition and histological structure of the tumor. Neoadjuvant chemotherapy for serous ovarian cancer according to the SAR scheme, in comparison with the CMFV scheme, leads to a significant improvement in the immediate results of treatment, increased operability and improved long-term results. Five-year survival of patients after neoadjuvant chemotherapy under the CAP scheme was 68 %, according to the CMFV scheme – 16 %.

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References:
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Keywords: serous ovarian cancer, chemotherapy, treatment outcomes


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Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy