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ISSN 2073-8137
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Treatment of cavitary bone defects under implantation of the mesh structures made of titanium nickelide

[Orthopedics and traumatology]
Yuri Iryanov; Nikolai Strelkov; Nikolai Kiryanov; Olga Dyuryagina;

The aim was to study the morphological features of reparative osteogenesis during implantation of the mesh structures made of titanium nickelide in the femoral metaphyseal defect. Cavitary defects of the femur metaphysis were modeled in the experimental and control group in adult male rats of the Wistar line. In animals of the experimental group, an implant was placed in the defect. X-ray, histology, scanning electron microscopy and X-ray electron probe microanalysis were used. It was found that the microporous surface of the implant provided osteoblast adhesion, osseointegration and adsorption of endogenous bone morphogenetic proteins. The implant possessed osteoconductive and osteoinductive properties, which stopped the inflammatory process. Biological membrane protective barrier in the periosteal zone of the defect around the implant prevents the germination of the connective tissue. Defect refunded cancellous bone, the bulk density of which was more than one and a half times higher than the benchmarks. The implant demonstrated expressed osteoplastic properties and can be successfully applied in orthopedic surgery.

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References:
1. Ir’janov Ju. M., Ir’janova T. Ju. Morfologiia. – Morphology. 2012;142(4):83-86.
2. Ir’janov Ju. M., Ir’janova T. Ju. Izobretenija. Poleznye modeli. – Gadgetry. Useful model. 2011;36: 27.12.2011.
3. Chernov V. F., Bevzjuk A. N., Chernov A. V., Ir’janov Ju. M. Med. nauka i obraz. Urala. – Medicine sciences and education of Ural. 2008;2:98-100.
4. Hämmerle C. H., Jung R. E. Periodontol 2000. 2003;33(1):36-53. doi: 10.1046/j.0906-6713.2003. 03304.x
5. Iriyanov Yu. M. Chernov V. F., Radchenko S. A., Chernov A. V. Bull Exp Biol Med. 2013;155(4):518-521. doi.org/10.1007/s10517-013-2191-4
6. Irianov Y. M., Diuriagina O. V., Karaseva T. Y., Karasev Е. А. Bosn. J. Basic Med. Sci. 2014;14(1):4-7.
7. Jung R. E., Fenner N., Hämmerle C. H., Zitzmann N. U. Clin. Oral. Implants Res. 2013;24(10):1065-1073. doi: 10.1111/j.1600-0501.2012.02522.x
8. Karring T., Nyman S., Gottlow J., Laurell L. Periodontol. 2000. 1993; 1(1):26-35. doi: 10.1111/j.1600-0757.1993. tb00204.x
9. Kim J. Y., Yang B. E., Ahn J. H., Park S. O., Shim H. W. J. Adv. Prosthodont. 2014;6(6):539-546. doi: 10.4047/ jap.2014.6.6.539
10. Liu J., Kerns D. G. Open Dent. J. 2014;16(8):56-65. doi: 10.2174/1874210601408010056
11. Schmidmaier G., Baehr K., Mohr S., Kretschmar M., Beck S., Wildemann B. Clin. Oral. Implants Res. 2006;17(4): 439-444. doi: 10.1111/j.1600-0501.2005.01242.x
12. Uebersax L., Hagenmüller H., Hofmann S., Gruenblatt E., Müller R., Vunjak-Novakovic G., Kaplan D. L., Merkle H. P., Meinel L. Tissue Eng. 2006;12(12):3417- 3429. doi: 10.1089/ten.2006.12.3417
13. van Leeuwen A. C., Huddleston Slater J. J., Gielkens P. F., de Jong J. R., Grijpma D. W., Bos R. R. Acta Biomater. 2012;8(4):1422-1429. doi: 10.1016/j.actbio. 2011.12.004

Keywords: implant, mesh constructions, titanium nickelide, bone defect, reparative osteogenesis


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