Site search
Correspondence address
310 Mira Street, Stavropol, Russia, 355017
Tel
+7 865 2352511, +7 865 2353229.
E-mail
medvestnik@stgmu.ru
The journal is included into The list of leading scientific periodicals.
The journal is included into VINITI database and is registered in Electronic scientific library.
The journal is indexed by SCOPUS, Ulrich's International Periodicals Directory.
[Clinical Pharmacology]
Vladimir Baturin; M. Selimov; Albert Bolatchiev; Roman Budkevich; Vladimir Sadovoy; Elena Kunitsyna;
With the use of high-resolution atomic force microscopy the effect of cefotaxime on morphological and mechanical properties of gram-positive bacteria (Staphylococcus aureus) cells was studied. The difference in the morphological features of bacterial populations was shown by the nature of the response to the antimicrobial agent. The common point was a decrease in diameter and an increase in the altitude characteristics of cells, which may be due to internal osmotic pressure on the cell wall, which reduced its rigidity under the action of cefotaxime.
References:
1. Baturin V. A., Shchetinin Ye. V., Demidenko I. F., Korableva O. A. Byulleten antibiotikorezistentnosti respiratornykh patogenov v OITAR g. Stavropolya. Stavropol: StGMU, 2014.
2. Erokhin P. S. Atomno-silovaya mikroskopiya kak instrument opredeleniya chuvstvitelnosti baktery k faktoram bioticheskoy i abioticheskoy prirody: avtoref. dis. kand. fiz.-mat. Nauk. Saratov, 2015.
3. Mironov V. L. Osnovy skaniruyushchey zondovoy mikroskopii. N. Novgorod, 2004.
4. Opredeleniye chuvstvitelnosti mikroorganizmov k antibakterialnym preparatam. Metodicheskiye ukazaniya. M., 2004.
5. Pleskova S. N. Dubrovin Ye. V., Golubeva I.S., Gorshkova Ye. N., Pudovkina Ye. E. Fizika tvyordogo tela. Vestnik Nizhegorodskogo universiteta im. N. I. Lobachevskogo. – Solid state physics bulletin of the Nizhny Novgorod University, N. I. Lobachevsky. 2013;2(2):34-38.
6. Prakticheskoye rukovodstvo po antiinfektsionnoy khimioterapiii. pod red. L. S. Strachunskogo, Yu. B. Belousova, S. N. Kozlova. Smolensk: «MAKMAKh», 2007.
7. Ratsionalnaya antimikrobnaya terapiya. pod red. S. V. Yakovleva. 2-e izd., pererab. i dop. M.:«Litterra», 2015.
8. Yaminsky I. V., Demin V. V., Bondarenko V. M. Zhurn. mikrobiologii. – Journal of microbiology. 1997;6:15-18.
9. Binnig G., Quate C. F., Gerber Ch. Phys Rev Lett. 1986;6(59):930-933.
10. Bondareva N. I., Timchenko L. D., Rzhepakovsky I. V. Res. J. Pharm., Biol. Chem. Sci. (RJPBCS). 2016;7(6):1224- 1230.
11. Finberg R. V., Moellering R. C., Tally F. P. Clin. Infect. Dis. 2004;(39):1314-1320.
12. Fuhrmann A., Ros R. Nanomedicine. 2010;5(4):657-665.
13. Fuchs P. C., Jones R. N., Thornsberry C., Barry A. L., Gerlach E. H., Sommers H. M. Antimicrob. Agents Chemother. 1981;20(6):747-759.
14. LeFrock J. L., Prince R. A., Leff R. D. Pharmacotherapy. 1982;2(4):174-184. doi: 10.1002/j.1875-9114.1982. tb03185
15. Martínez J. L., Baquero F. Ups. J. Med. Sci. 2014;119(2): 68-77. doi: 10.3109/03009734.2014.901444
16. Meyer R. L. Zhou X., Tang L. Ultramicroscopy. 2010;110(11):1349-1357. doi: 10.1016/j.ultramic. 2010.06.010
17. Nikiyan A., Vasilchenko A., Deryabin D. Intern. J. Microbiol. 2010. doi:10.1155/2010/704170
18. Volle C. B., Ferguson M. A., Aidala K. E., Spain E. M., Nunez M. E. Coll. Surf. B Biointerfaces. 2008;67(1): 32-40.
19. Saranya S., Hemashenpagam N. Sci. Res. 2011;2(4): 528-534.
20. Smirnova M. V., Lubenko I. Yu. Intern. J. Antimicrobial Agents. 2007;29(2):165-169.
Keywords: cefotaxime, atomic force microscopy, Staphylococcus aureus, bacterial cells morphometry