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of the North Caucasus
Scientific journal
Mass media registration certificate dated December 7, 2006.
Series ПИ #ФС 77-26521.
Federal service for surveillance over non-violation of the legislation in the sphere of mass communications and protection of cultural heritage.
ISSN 2073-8137
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Significance of endothelial dysfunction in early diagnostics of diabetic nephropathy in children and adolescents with type 1 diabetes

[Original research] [Pediatrics]
Tatyana Anikeeva; Evgeny Volchansky;

Reoangiography study was used to assess endothelial function. Estimation of endothelium-dependent vasodilation and endothelium-independent vasoconstriction was performed in 155 children and teenagers with type 1 diabetes and an early stage of diabetic nephropathy. High information value of endothelial dysfunction in diagnostics of microangiopathy and diabetic nephropathy has been demonstrated.

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Keywords: type 1 diabetes, diabetic nephropathy, endothelial dysfunction, endothelium-dependent vasodilation, endothelium-independent vasoconstriction


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Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy