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[Experimental medicine]
Zalina Kisieva; Vadim Brin;
The aim of the study was to investigate the prophylactic effect of Mildronat and Atsizol on morphological and functional renal parameters in animals undergone the native sheep plasma injection.
In the experiment, the simultaneous injection of Acyzol and Mildronat since the early period of the native sheep plasma injection contributes to the reduction of the amyloid nephropathy manifestations. We detected less severely impaired renal filtration capacity, tubular water reabsorption, sodium and potassium and calcium excretion, reduction of proteinuria. Histological study of the kidneys, heart, liver and spleen tissue revealed a decreased amyloid accumulation in the stromal-vascular structures.
References:
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8. Sokolovskij N. V. Sovremennye problemy nauki i obrazovaniya. – Modern problems of science and education. 2014;1. URL: www.science-education. ru/115-12250
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Keywords: amyloid nephropathy, potassium and calcium excretion, renal filtration capacity, tubular water reabsorption