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Group and rhesus identity of the blood of healthy and cerebral palsy children in the population of the Rostov region

[Original research] [Pediatrics]
Vladimir Tupikov; Viktor Shamik;

In order to investigate possible correlations of blood group and Rh factor with susceptibility to cerebral palsy and the risk of its occurrence, we examined data on group and Rh blood types (markers) of 3069 people, divided into 4 groups (children with cerebral palsy and their parents, healthy children and their parents). There is good evidence of a significant prevalence of A (II) Rhesus + (positive) blood group in children with cerebral palsy, as well as the significant effect of group and Rh blood type on the incidence of cerebral palsy. The risk of infantile cerebral palsy among the holders of the phenotype A (II) Rh + of the blood group and a gene p (A) 1.2 – 2.5 times exceeds the risk of the holders of other groups and genes of blood. These data point to the involvement of genetic and hereditary factors in the etiopathogenesis of infantile cerebral palsy and can be used for medical and genetic counseling, early formation and monitoring of children at risk for infantile cerebral palsy, planning of preventive, diagnostic and therapeutic measures.

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Keywords: blood group, infantile cerebral palsy