of the North Caucasus
Series ПИ #ФС 77-26521.
Federal service for surveillance over non-violation of the legislation in the sphere of mass communications and protection of cultural heritage.
ISSN 2073-8137
русский
english
Site search
Correspondence address
310 Mira Street, Stavropol, Russia, 355017
Tel
+7 865 2352511, +7 865 2353229.
E-mail
medvestnik@stgmu.ru
The journal is included into The list of leading scientific periodicals.
The journal is included into VINITI database and is registered in Electronic scientific library.
The journal is indexed by SCOPUS, Ulrich's International Periodicals Directory.
Neonatal sepsis caused by klebsiella
[Pediatrics]
Halit Haertynov; Vladimir Anokhin; Irina Nikolaeva; Dina Semenova; Sergey Lubin; Irina Agapova; Alsu Muginova; Gulshat Hasanova;
The main manifestation of neonatal sepsis was the hemorrhagic syndrome, which was diagnosed in 7 children. Thrombocytopenia of different severity was detected in all cases. Organ pathology was observed in seven cases. Three children suffered from septicemia (one of them developed toxic shock). No patients reported increased body temperature. K. pneumoniae, producing β-lactamase of extended spectrum, was isolated from the blood of six children (60 %). All patients had laboratory evidence of systemic inflammatory reaction. The hemorrhagic syndrome determined the severity of the disease in the majority of cases. Thrombocytopenia is one of the early diagnostic markers of neonatal sepsis caused by Klebsiella.
References:
1. Samsygina G. A. Pediatrija – Pediatrics. 2012;91(3):32-37.
2. Samsygina G. A. Neonatal’nyj sepsis. Moskva; 2014. 173 р.
3. Sidorenko S. V. Infekcija i antimikrobnaja terapija – Infection and antimicrobial therapy. 2002;6:164-170.
4. Stratchounski L. S. Klinicheskaya mikrobiologiya i antimikrobnaya khimioterapiya – Clinical Microbiology and Antimicrobial Chemotherapy. 2005;7(1):92-96.
5. Alyssa, S. S., Rajinder, P. S. B., Thomas, A. R. Virulence. 2013;4(2):107-118. doi: 10.4161/viru.22718.
6. Broberg C. A., Palacios M., Miller V.L. F1000Prime Reports. 2014;6(64). doi: 10.12703/P6-64.
7. Dong Y., Speer C. P. Arch. Dis. Child. Fetal. Neonatal. Ed. 2014;0:F1-F7. doi: 10.1136/archdischild- 2014-30621305.
8. Hornik C. P., Fort P., Clark R. H., Watt K., Benjamin D. K., Smith P. B., Wolkowiez M. C., Manzoni P., Jacqz-Aigrain E., Kaguelidou F., Cohen-Wolkowiez M. Early Hum Dev. 2012;88(2):69-74.
9. Stoll B. J., Hansen N. I., Sanchez P. J., Faix R. G., Poindexter B. B., Meurs K. P. V., Bizzarro M. J., Goldberg R. N., Frantz I. D. Pediatrics. 2011;127(5):817-826
10. Aguilar A., Merino S., Rubires X., Tomas J. M. Infect. Immun. 1997;65:1245-1250.
11. Janda J. M., Abbott S. L. The Enterobacteria. 2006. Washington; USA: ASM Press. Р. 115-129.
12. Kanj S. S., Kanafani Z. A. Mayo Clin Proc. 2011;86(3):250-259.
13. Lawn J. E., Cousens S., Zupan J. T. Lancet. 2005;365(9462):891-900.
14. Bei Li, Yuling Zhao, Changting Liu P., Zhenhong Chen. Future Microbiol. 2014;9(9):P.1071-1081. doi: 10.2217/ fmb.14.48.
15. Reinhart K., Bauer M., Riedemann N. C., Hartog C. S. Clin Microbiol Rev. 2012;25(4):609-634.
16. Podschun R., Ullmann U. Clinical Microbiology Reviews. 1998;4(11):589-603.
17. Sivanandan S., Soraisham A. S., Swarnam K. International Journal of Pediatrics. 2011. doi:10.1155/2011/712150.
18. Arif S. H., Ahmad I., Ali S. M., Khan H. M. Indian J. Hematol. Blood Transfus. 2012;28(3):147-151. doi:10.1007/s12288-011-0118-7.
Keywords: neonatal sepsis, Klebsiella, hemorrhagic syndrome
Founders:
Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy