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Series ПИ #ФС 77-26521.
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ISSN 2073-8137
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Endothelial dysfunction and melatonin

[Reviews]
Eduard Arushanyan; Evgeny Shchetinin;

The item offers independent and referential data on the role that melatonin plays in the regulation of endothelial function. There is also an analysis of the impact that melatonin has on cardiovascular system activity, which is related to restriction of arterial hypertension, atherosclerosis, metabolic syndrome with hyperlipidemia and diabetes mellitus, and enhanced platelet hemostasis. There is a discussion of a set of mechanisms on the cellular level (counteraction to oxidative stress) as well as on the systemic level – psychotropic and chronotropic effects of melatonin.

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Keywords: melatonin, endothelial dysfunction


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Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy