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Obesity and allergic diseases in children living in Stavropol

[Original research] [Pediatrics]
Villi Lysogora; Valentina Gervazieva;

Observational and analytical study of the «case-control» type based on a retrospective analysis of case histories of children with allergic diseases, living in the city of Stavropol was carried out in order to clarify the relationship of obesity and allergy. Case histories of 214 children (120 boys and 94 girls) aged 12-17, with rhinitis/rhinoconjunctivitis, atopic dermatitis in combination with bronchial asthma (BA) and without it were taken. According to the body mass index the children were divided into three weight categories: 73 (34%) people with normal weight, 74 (35%) – overweight people and 67 (31%) – those with obesity. It turned out that obesity is prevalent in children of 12-14 years old, decreasing to 17 years of age. No significant relationship of obesity with a sex of the child and allergies has been identified, but there was a trend for more frequent detection of obesity in boys.

The children with allergies and asthma 3 times more often had overweight and obesity. But in children with allergic diseases and obesity high level of total IgE is about 4 times more common than in children of normal weight. The relationship of overweight and obesity with atopy was also confirmed by the association in children of these weight categories of elevated levels of specific IgE-antibodies to a wide range of pollen, food, epidermal allergens and dust mite allergens.

Thus, overweight and obesity in children with allergic diseases are more associated with atopic asthma and may be considered as risk factors for poor prognosis in allergy.

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References:
1. Vlasov V.V. Epidemiologiya. – M.: «GEOTAR-Media»; 2006;4.
2. Grzhibovsky A.M. Ekologiya cheloveka. – Нuman ecology. 2008;6:58-68.
3. Gushchin I.S., Kurbacheva O.M. Allergiya i allergenspetsificheskaya immunoterapiya. M.: «Farmarus Print Media». 2010;228
4. Appleton S.L., Adams R.J., Wilson D.H. et al. J Allergy Clin Immunol. 2006;118:1284-1291.
5. Barton M. Acta Pharmacol Sin. 2012;33(2):189-193.
6. Barton M., Baretella O., Meyer M.R. Br J Pharmacol. 2012;165(3):591-602.
7. Ciprandi G., Pistorio A., Tosca M. et al. Res Medicine. 2009;103:289-295.
8. Creely S.J., McTernan P.G., Kusminski C.M. et al. Am J Physiol Endocrinol Metab. 2007;292(3):740-747.
9. Gorgievska-Sukarovska B., Lipozencić J., Susac A. Acta Dermatovenerol Croat. 2008;16(4):231-235.
10. Jarvis D., Chinn S., Potts J., Burney P. Clin Exp Allergy. 2002;32(6):831-837.
11. Jensen M.E., Woocf L.G., Gibson P.G. Curr Opin Allergy Clin Immunol. 2012;12:186-192.
12. Leung T.F., Kong A.P., Chan I.H. et al. Int Arch Allergy Immunol. 2009;149(2):133-140.
13. Okabe Y., Itazawa T., Adachi Y. et al. Pediatr Int. 2011;53(2):192-198.
14. Pataky Z., Bobbioni-Harsch E., Golay A. Exp Clin Endocrinol Diabetes. 2010;118(7):427-433.
15. Rochat M.K., Illi S., Ege M.J. et al. J Allergy Clin Immunol. 2010;126(6):1170-1175.
16. Schaffler А., Scholmerich J., Salzberger B. TRENDS in Immunology. 2007;28(9):393-399.
17. Scheinmann P., Pham Thi N., Karila C., de Blic J. Arch Pediatr. 2012;19(3):330-345.
18. Silverberg J.I., Kleiman E., Lev-Tov H. et al. J Allergy Clin Immunol. 2011;127:1180-1186.
19. Spergel J.M. Ann Allergy Asthma Immunol. 2010;105(2):99-106.
20. Visness C.M., London S.J., Daniels J.L. et al. J Asthma. 2010;47(7):822-829.
21. Visness C.M., London S.J., Daniels J.L. et al. Allergy Clin Immunol. 2009;123:1163-1169.
22. Yu S., Kim H.B., Lee S.Y. et al. Int Arch Allergy Immunol. 2011;154(1):42-48.

Keywords: obesity, allergic diseases, bronchial asthma, IgE, IgE-antibodies, children