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[Original research] [Pediatrics]
Anastasia Medvedeva; Angelina Kalmykova;
The population subject to the study included 220 children aged 1 month – 5 years, with acute community acquired infections of the upper and lower urinary tract. As the data obtained showed, the major agents causing community acquired UTI in the first 5 years of age were bacteria belonging to the Enterobacteriaceae family, E. coli predominantly. The major features in the structure of the agents responsible for UTI development in the children of Stavropol (Russia) were higher detection frequency of Str.faecalis, which was the second most common in all the groups examined, while the children aged с 3–5 had it 1.8–2.9 times as often.
In view of the leading etiological significance of Enterobacteriaceae as well as taking into account the obtained data on the pathogens susceptibility towards antibiotics, Amoxiclav, Cefotaxime, Cefoperazone, Ceftazidime, Cefepime, and Meropenem make a reasonable choice as empiric therapy for treating community acquired UTI in children aged up to 5. The penicillin antibiotics (Ampicillin, Amoxicillin, Oxacillin) and Laevomycetin should not be administered for empiric treatment due to the high-level resistance Enterobacteriaceae revealed towards them.
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Keywords: children, urinary tract infection, sensitivity, antibiotic drugs