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[Experimental medicine]
Vadim Brin; Astan Mitziev; Karmen Mitziev;
The aim was to investigate possible alteration of tubular apparatus sensitivity to vasopressin and its prevention by melaxen in chronic lead poisoning. Preventive application of melaxen reduces the severity of lead acetate toxic effects resulting in maintenance of renal sensitivity to antidiuretic hormone and consequence reduction of water excretion percent.
References:
1.Brin V. B., Mittsiev A. K., Mittsiev K. G. Vestnik novyh medicinskih tehnologij. Bulletin of the new medical technologies. 2012;19(1):166-168.
2.Mittsiev A. K. Kubanskij nauchnyj medicinskij vestnik. – Kuban medical scientific Herald. 2008;(6):32-36.
3.Barbier O., Jacquillet G., Tauc M., Cougnon M., Poujeol P. Nephron Physiol. 2005;99(4):105-110.
4.Gagan F., Deepesh G., Archana T. Interdiscip Toxicol. 2012;5(2):47-58.
5.Sabath E., Robles-Osorio M. L. Nefrologia. 2012;32(3):279-286.
6.Sabolih I. Nephron Physiol. 2006;104(3):107-114.
Keywords: lead poisoning, vasopressin, melaxen, kidneys