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[Original research] [Surgery]
Roman Kalinin; Igor Suchkov; Alexandr Pshennikov; Alexandr Slepnyov;
The article represents data on efficacy of different drugs in prevention of restenosis after lower limb arterial reconstructive surgery. The efficacy of L-arginine, perindopril, losartan and nebivolol was evaluated in comparison with the control group. The incidence of neointimal hyperplasia and bypass thrombosis was found to be lower in the cases of endothelium directed therapy.
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Keywords: nitric oxide, neointimal hyperplasia, restenosis, endotheliotropic therapy